Leveraging high-resolution structural techniques to visualize and understand the function and mechanisms of biological molecules, with an emphasis on proteins. The course covers the theory of modern x-ray diffraction and electron microscopy for macromolecules, provides hands-on experimentation with both techniques, and presents case studies from the literature to highlight how these techniques can be leveraged to reveal the mechanisms of action of some of nature's most powerful catalysts. The course is open to upper-level undergrads, co-terms, and graduate students. This is the lecture section. Students interested in enrolling in the lab companion section, please contact Dr. Christopher Barnes to enroll in BIO 218A (lab section).
3 units · Letter or Credit/No Credit
Leveraging high-resolution structural techniques to visualize and understand the function and mechanisms of biological molecules, with an emphasis on proteins. The course covers the theory of modern x-ray diffraction and electron microscopy for macromolecules, provides hands-on experimentation with both techniques, and presents case studies from the literature to highlight how these techniques can be leveraged to reveal the mechanisms of action of some of nature's most powerful catalysts. The course is open to upper-level undergrads, co-terms, and graduate students. This is the lecture section. Students interested in enrolling in the lab companion section, please contact Dr. Christopher Barnes to enroll in BIO 218A (lab section).