This mini course will explore structural variants (SVs) in genomes, an emerging topic with applications to many biological sub-disciplines. New sequencing technologies and computational techniques are unlocking this formerly hidden class of genomic diversity and revealing the importance of these variants in both disease and adaptation. In a series of lectures and workshops, the course will cover a brief history of the field, distribution of SVs in genomes, relevance of SVs to both disease and adaptation, recent methods to identify and resolve SVs, and future outlooks and approaches. Prerequisites: some background with genetics. Familiarity with a Unix/Linux environment would be helpful.
3 units · Medical Satisfactory/No Credit
This mini course will explore structural variants (SVs) in genomes, an emerging topic with applications to many biological sub-disciplines. New sequencing technologies and computational techniques are unlocking this formerly hidden class of genomic diversity and revealing the importance of these variants in both disease and adaptation. In a series of lectures and workshops, the course will cover a brief history of the field, distribution of SVs in genomes, relevance of SVs to both disease and adaptation, recent methods to identify and resolve SVs, and future outlooks and approaches. Prerequisites: some background with genetics. Familiarity with a Unix/Linux environment would be helpful.
Offered in Winter 2027 at Stanford University.