Stanford Root

Schedule

Stanford Root

Schedule

GENE 246

Synthetic proteins and genetic circuits (BIO 246, BIOE 266)

UNITS:2
GRADING:Medical Option (Med-Ltr-CR/NC)
LEVEL:Graduate
GER:—

Synthetic proteins and gene circuits are rapidly evolving technologies that are increasingly central to research and medicine. These proteins and gene circuits are core to next-generation medicines as biologics and cell therapies, research tools that give us unprecedented control over biological processes, and serve as powerful industrial tools. Through lecture and discussion of literature, we will explore key concepts including modularity in synthetic biology, methods of protein and circuit design, and practical applications. We will also discuss how directed evolution, high-throughput screening, and machine learning/artificial intelligence might reshape the landscape of synthetic proteins and gene circuits.

Syllabus for selected term:
View Autumn 2026 Syllabus

Sections

1 Term
Lecture 1Open
ID: 14098
0 / 45 enrolled
DAYS:Wednesday
TIME:12:30 PM – 2:20 PM
LOCATION:Hewlett Teaching Center Rm 101
INSTRUCTOR:
Brophy, Jennifer, Daniels, Kyle
2units

GENE 246: Synthetic proteins and genetic circuits (BIO 246, BIOE 266)

2 units · Medical Option (Med-Ltr-CR/NC)

Synthetic proteins and gene circuits are rapidly evolving technologies that are increasingly central to research and medicine. These proteins and gene circuits are core to next-generation medicines as biologics and cell therapies, research tools that give us unprecedented control over biological processes, and serve as powerful industrial tools. Through lecture and discussion of literature, we will explore key concepts including modularity in synthetic biology, methods of protein and circuit design, and practical applications. We will also discuss how directed evolution, high-throughput screening, and machine learning/artificial intelligence might reshape the landscape of synthetic proteins and gene circuits.

Offered in Autumn 2026 at Stanford University.

Autumn 2026 sections

  • Lecture — Wednesday 12:30 PM – 2:20 PM — Hewlett Teaching Center Rm 101 — Brophy, Jennifer, Daniels, Kyle (Graduate)

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  • GENE 231: AI and Vibecoding for healthcare (GENE 131)
  • GENE 232: Advanced Imaging Lab in Biophysics (APPPHYS 232, BIO 132, BIO 232, BIOE 232, BIOPHYS 232)
  • GENE 236: Deep Learning in Genomics and Biomedicine (BMDS 273, CS 273B)
  • GENE 237: Precision Health & Wellbeing
  • GENE 242: Genetics of Viral Emergence and Emerging Viruses
  • GENE 247: Genomic approaches to the study of human disease (BIO 127, BIO 247)
  • GENE 260: Supervised Study
  • GENE 268: Biology and Applications of CRISPR/Cas9: Genome Editing and Epigenome Modifications (BIOS 268)
  • GENE 271: Human Molecular Genetics and Cytogenetics
  • GENE 272: Introduction to Medical Genetics
  • GENE 273: Introduction to Clinical Genetics Testing

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